Buckhorn Mountain is located on the historic "North Half" of the Colville Indian Reservation in North Central Washington, just south of the Canadian border on the Okanogan National Forest between the Cascades and the Kettle Range. Five perennial creeks (Bolster, Gold, Ethel, Marias and Nicholson) that originate on Buckhorn Mountain flow into two basins (Myers and Toroda Creeks) before flowing into the Kettle River in Canada and eventually into the the Columbia.

Buckhorn is home to a great diversity of plant and wildlife species, including several rare, sensitive or endangered species. It continues to be a favorite place for hunting, fishing and outdoor recreation. Aspen meadows, conifer forests and spruce bogs blend with dry grassy hillsides resplendent with wildflowers.